Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Apolipoprotein D.

E Rassart1, A Bedirian, S Do Carmo

  • 1Département des Sciences Biologiques, Université du Québec à Montréal, Canada. rassart.eric@uqam.ca

Biochimica Et Biophysica Acta
|November 4, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CRISPR-based oligo recombineering prioritizes apicomplexan cysteines for drug discovery.

Nature microbiology·2022
Same author

Involving research participants in a pan-European research initiative: the EPAD participant panel experience.

Research involvement and engagement·2020
Same author

[Better Reporting of Interventions: Template for Intervention Description and Replication (TIDieR) Checklist and Guide].

Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))·2018
Same author

Ethical Issues in the Development of Readiness Cohorts in Alzheimer's Disease Research.

The journal of prevention of Alzheimer's disease·2017
Same author

BACE1 inhibition by microdose lithium formulation NP03 rescues memory loss and early stage amyloid neuropathology.

Translational psychiatry·2017
Same author

[Better Reporting of Interventions: Template for Intervention Description and Replication (TIDieR) Checklist and Guide].

Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))·2016
Same journal

Cumulative Contents.

Biochimica et biophysica acta·2020
Same journal

Molecular Basis of Disease Cumulative Contents.

Biochimica et biophysica acta·2020
Same journal

General Subjects Cumulative Contents.

Biochimica et biophysica acta·2020
Same journal

Erratum to 'on the role of exchangeable hydrogen bonds for the kinetics of P680<sup>+·</sup> Q<sub>A</sub> <sup>-·</sup> formation and P680<sup>+·</sup> Pheo<sup>-·</sup> recombination in photosystem II' [Biochim. Biophys. Acta 1276 (1996) 35-44].

Biochimica et biophysica acta·2019
Same journal

Oligomeric state of the light-harvesting complexes B800-850 and B875 from purple bacterium Rubrivivax gelatinosus in detergent solution.

Biochimica et biophysica acta·2019
Same journal

Regulation of pigment content and enzyme activity in the cyanobacterium Nostoc sp. Mac grown in continuous light, a light-dark photoperiod, or darkness.

Biochimica et biophysica acta·2019
See all related articles

Apolipoprotein D (apoD) is a lipocalin protein that transports various molecules. Its roles in metabolism and tissue repair, particularly in the nervous system, are being investigated.

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Neuroscience

Background:

  • Apolipoprotein D (apoD) is a glycoprotein associated with high-density lipoproteins.
  • Structurally, apoD belongs to the lipocalin family, known for transporting hydrophobic ligands.
  • Its precise physiological ligands and functions remain largely undefined.

Purpose of the Study:

  • To explore the potential roles and functions of Apolipoprotein D.
  • To investigate apoD's involvement in metabolism and tissue maintenance/repair.

Main Methods:

  • Analysis of apoD's structural properties as a lipocalin.
  • Examination of apoD expression patterns in various tissues.
  • Observation of apoD accumulation in specific physiological and pathological conditions.

Related Experiment Videos

Main Results:

  • ApoD exhibits binding capabilities for cholesterol, progesterone, and other molecules, though physiological relevance is unclear.
  • High apoD expression is noted in spleen, testes, and brain.
  • ApoD accumulates in breast cyst fluid and in areas of nerve regeneration and neurodegeneration (e.g., Alzheimer's disease).

Conclusions:

  • Apolipoprotein D is a multi-ligand, multi-functional transporter with potential roles in the central and peripheral nervous systems.
  • Further research is needed to define apoD's exact role in metabolism and its precise transport functions.