Acute pancreatitis in a child with idiopathic ulcerative colitis on long-term 5-aminosalicylic acid therapy

A C Paul1, S P Oommen, S Angami

  • 1Department of Child Health, Christian Medical College Hospital, Vellore.

Insights

Acute pancreatitis is a rare complication of inflammatory bowel disease. This case highlights a pediatric ulcerative colitis patient developing pancreatitis during 5-aminosalicylic acid treatment.

Area of Science:

  • Gastroenterology
  • Pediatric Gastroenterology
  • Clinical Medicine

Background:

  • Inflammatory bowel disease (IBD) encompasses chronic gastrointestinal conditions.
  • Acute pancreatitis is an uncommon complication of IBD in adults.
  • Pancreatitis in pediatric IBD patients is exceptionally rare.

Observation:

  • A 10-year-old boy diagnosed with ulcerative colitis was studied.
  • The patient had been receiving long-term 5-aminosalicylic acid (5-ASA) medication.
  • The child developed acute pancreatitis during his treatment course.

Findings:

  • This case presents a rare instance of acute pancreatitis in a pediatric patient with ulcerative colitis.
  • The pancreatitis occurred during established treatment with 5-aminosalicylic acid.
  • This suggests a potential link between 5-ASA and pancreatitis in this demographic.

Implications:

  • Clinicians should consider pancreatitis in pediatric IBD patients presenting with abdominal pain.
  • Further investigation into the association between 5-ASA and pancreatitis in children is warranted.
  • This finding may inform treatment guidelines for pediatric ulcerative colitis.

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