Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sepsis in children.

K Oda1, Y Matsuo, K Nagai

  • 1Department of Pediatrics and Child Health, Kurume University School of Medicine, Fukuoka, Japan. tsumura@ha.bekkoame.ne.jp

Pediatrics International : Official Journal of the Japan Pediatric Society
|November 4, 2000
PubMed
Summary

Pediatric sepsis is a significant concern, with most cases occurring in hospitalized children with underlying conditions. Gram-positive bacteria, particularly Staphylococcus aureus, were common, but Gram-negative sepsis showed higher mortality rates.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adenosine A2 receptor antagonist facilitates the reversal of long-term potentiation (depotentiation) of evoked postsynaptic potentials but inhibits that of population spikes in hippocampal CA1 neurons.

Neuroscience letters·1992
Same author

The helix-loop-helix/leucine repeat transcription factor USF can be functionally regulated in a redox-dependent manner.

The Journal of biological chemistry·1992
Same author

Immunohistochemical study of the histogenesis of esophageal carcinosarcoma.

Japanese journal of clinical oncology·1992
Same author

Structure and distribution of the lymphatic vessels in the parietal pleura of the monkey as studied by enzyme-histochemistry and by light and electron microscopy.

Archives of histology and cytology·1992
Same author

Specific expressions of Fyn and Lyn, lymphocyte antigen receptor-associated tyrosine kinases, in the central nervous system.

Brain research. Molecular brain research·1992
Same author

A hyperpolarizing response induced by glutamate in mouse cerebellar Purkinje cells.

Neuroscience research·1992

Area of Science:

  • Pediatric infectious diseases
  • Clinical microbiology
  • Hospital epidemiology

Background:

  • Sepsis poses a significant mortality risk to children.
  • Approximately 2% of all hospitalized patients at the institution experienced sepsis.
  • The study focused on analyzing sepsis episodes within the ward.

Purpose of the Study:

  • To analyze the characteristics and outcomes of sepsis episodes in hospitalized children.
  • To identify common causative agents and risk factors associated with pediatric sepsis.
  • To understand the impact of underlying diseases and specific pathogens on sepsis mortality.

Main Methods:

  • Retrospective review and analysis of sepsis cases from January 1984 to December 1998.
  • Inclusion of 366 sepsis episodes in 244 admitted pediatric patients.

Related Experiment Videos

  • Identification of causative agents, underlying diseases, and complications.

    • Main Results:

    • Sepsis occurred in approximately 2% of hospitalized patients, with 43% of cases in children under 1 year old.
    • Eighty-seven percent of patients had underlying diseases, most commonly hematologic disorders or neoplasms.
    • Gram-positive bacteria (68%) were the most frequent causative agents, with Staphylococcus aureus being the most common organism; however, Gram-negative sepsis had higher mortality.

    Conclusions:

    • Nearly 20% of septic pediatric patients were under 1 year of age, and 90% had underlying diseases.
    • The specific causative agents of sepsis significantly influenced patient outcomes.
    • Hospital-acquired sepsis was prevalent, highlighting the need for infection control measures.