[Stereotaxic biopsy of cerebral subcortical structures in parkinsonism]

The design-features of a stereotaxic cannula for biopsy of subcortical cerebral structures and the procedure for performing stereotaxic biopsy are described. A total of 9 stereotaxic biopsies of the ventro-lateral thalamic nucleus, median center and globus pallidus were effected. As illustrated by a number of electronograms the material obtained during operations proved to be completely intact and suitable for electron microscope examinations. Ways and objectives for analyzing the ultrastructure of subcortical formations in parkinsonism and other hyperkineses are outlined.