Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

William Hogarth, unwitting neurochemist?

B W Agranoff1

  • 1Mental Health Research Institute and Department of Biological Chemistry, University of Michigan, Ann Arbor 48104-1687, USA.

Neurochemical Research
|November 4, 2000
PubMed
Summary

William Hogarth

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The retina as a biochemical model of central nervous system regeneration.

Neurochemistry international·2010
Same author

Inositol, lithium, and the brain.

Psychopharmacology bulletin·2002
Same author

Regulation of Myo-inositol homeostasis in differentiated human NT2-N neurons.

Neurochemical research·2000
Same author

Increased expression of Galpha(q/11) and of phospholipase-Cbeta1/4 in differentiated human NT2-N neurons: enhancement of phosphoinositide hydrolysis.

Journal of neurochemistry·2000
Same author

A vulnerable period of colchicine toxicity during goldfish optic nerve regeneration.

Brain research·1999
Same author

Cloning and characterization of zRICH, a 2',3'-cyclic-nucleotide 3'-phosphodiesterase induced during zebrafish optic nerve regeneration.

Journal of neurochemistry·1999

Area of Science:

  • Neuroscience
  • Art History
  • Sociology

Background:

  • William Hogarth's 18th-century etchings, "Gin Lane" and "Beer Street," offer a stark visual contrast between the effects of alcohol addiction and moderate consumption.
  • "Gin Lane" depicts the devastating consequences of distilled spirit addiction, including malnutrition and brain dysfunction.
  • "Beer Street" illustrates a healthier society, suggesting the benefits of less potent alcoholic beverages.

Discussion:

  • Modern neurochemical research elucidates the mechanisms by which malnutrition, particularly avitaminosis, from distilled spirit addiction disrupts brain metabolism and function.
  • The study links historical artistic representations of alcohol's effects to contemporary scientific understanding of neurochemical disturbances.
  • Comparing the societal impacts depicted in "Gin Lane" and "Beer Street" provides a historical perspective on alcohol-related health issues.

Key Insights:

  • Alcohol addiction, especially to distilled spirits, leads to malnutrition and significant disturbances in brain metabolism and function.
  • Neurochemical research validates the long-observed sociological and clinical relevance of alcohol's impact on health and behavior.
  • The contrasting etchings serve as enduring illustrations of the differential health outcomes associated with various patterns of alcohol consumption.

Outlook:

  • Further research can explore the specific neurochemical pathways affected by alcohol-induced malnutrition.
  • The findings can inform public health strategies and clinical interventions for alcohol addiction.
  • Continued interdisciplinary study integrating art, history, and neuroscience can offer novel insights into human behavior and health.

Related Experiment Videos