Related Experiment Videos
Percutaneous transcatheter aortic disc valve prosthesis implantation: a feasibility study
J Sochman1, J H Peregrin, D Pavcnik
1Department of Cardiology, Institute for Clinical and Experimental Medicine, Vídenská 1958/9, 140 21 Prague 4, Czech Republic.
Purpose:
Over the past 30 years there have been experimental efforts at catheter-based management of aortic valve regurgitation with the idea of extending treatment to nonsurgical candidates. A new catheter-based aortic valve design is described.
Methods:
The new catheter-delivered valve consists of a stent-based valve cage with locking mechanism and a prosthetic flexible tilting valve disc. The valve cage is delivered first followed by deployment and locking of the disc. In acute experiments, valve implantation was done in four dogs.
Results:
Valve implantation was successful in all four animals. The implanted valve functioned well for the duration of the experiments (up to 3 hr).
Conclusion:
The study showed the implantation feasibility and short-term function of the tested catheter-based aortic disc valve. Further experimental studies are warranted.