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Genomic structure and chromosome mapping of human and mouse RAMP genes
C Derst1, H Engel, K Grzeschik
1Institute for Normal and Pathological Physiology, Marburg University, Marburg, Germany.
Cytogenetics and Cell Genetics
|November 4, 2000
Abstract:
The cDNAs for human and murine Receptor Activity Modifying Proteins and for the associated murine Calcitonin Receptor Like Receptor were isolated. The human RAMP1 and RAMP3 genes possess two introns and human RAMP2 possesses three introns. Human RAMP1 was assigned to chromosome 2q36-->q37.1, RAMP2 to 17q12-->q21.1 and RAMP3 to 7p13-->p12. Mouse Ramp1 was assigned to chromosome 1 and Ramp2 and Ramp3 were assigned to chromosome 11.