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Esophageal cast: a manifestation of graft-versus-host disease

I M Nakshabendi1, M E Maldonado, D Coppola

  • 1Division of Digestive Diseases and Nutrition, University of South Florida College of Medicine, Tampa, Florida 33612-4799, USA. ianaksh@com1.med.usf.edu

Diffuse involvement of the gastrointestinal tract by graft-versus-host disease (GVHD) is a common complication of bone marrow transplantation. The esophageal involvement in this disease tends to be a vesiculobullous, ulcerative or desquamative process. To our knowledge, esophageal cast has not been described in the context of GVHD. However, it has been described as a result of trauma to the esophagus or in association with bullous disease of the skin. We present a case of esophageal cast in a patient with chronic GVHD following bone marrow transplant.

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