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Updated: Aug 19, 2026

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology
Published on: October 21, 2010
[Lympho-gammagraphy and study of sentinel node in cutaneous melanoma]
M V Fliquete Peris1, J Giménez Climent, C Vázquez Forner
1Servicio de Medicina Nuclear. Fundación Instituto Valenciano de Oncología. Valencia.
Objective:
To evaluate the role of selective sentinel lymph node dissection to reduce the number of unnecessary lymphadenectomies in patients with intermediate risk of melanoma and without clinical evidence of regional node and distant metastases.
Material And Method:
We studied 65 patients with stage I and II melanoma. Only vital blue dye mapping was carried out in nine patients and combined lymphatic mapping with both blue dye and lymphoscintigraphy was used in the remaining 56 patients.
Results:
The sentinel node was identified in 63 of 65 patients (97%). Only eighth patients (12%) were found to have metastatic melanoma cells in their sentinel node.
Conclusions:
Our findings confirm that the intraoperative lymphatic mapping of the sentinel node using both blue dye and radiodetection is an appropriate and simple technique for selecting patients who are more likely to benefit from lymph node dissection.
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