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Murine Surgical Model of Topical Elastase Induced Descending Thoracic Aortic Aneurysm
Published on: August 24, 2019
Surgical Management of Giant Descending Aortic Thrombus Detected by Transesophageal Echocardiography
1Department of Surgery, Section of Cardiothoracic Surgery, Yale University School of Medicine, New Haven, Connecticut
Insights
Giant aortic thrombi, increasingly detected with transesophageal echocardiography (TEE), can cause peripheral emboli. Surgical removal and anticoagulation effectively treated three patients with unexplained emboli from descending aorta thrombi.
Area of Science:
- Cardiovascular Medicine
- Vascular Surgery
- Diagnostic Imaging
Background:
- Giant thrombi in the descending aorta are increasingly identified as a source of peripheral emboli.
- Transesophageal echocardiography (TEE) has improved the recognition of these aortic thrombi.
Purpose of the Study:
- To describe the successful management of patients with multiple unexplained peripheral emboli originating from descending aorta thrombi.
Main Methods:
- Case series of three patients presenting with unexplained peripheral emboli.
- Diagnostic evaluation including transesophageal echocardiography (TEE).
- Surgical intervention: aortic thrombectomy.
- Long-term anticoagulation therapy.
Main Results:
- Identification of giant descending aorta thrombi as the source of emboli in all three patients.
- Successful treatment with aortic thrombectomy.
- Absence of recurrent embolic events with long-term anticoagulation.
Conclusions:
- Giant descending aorta thrombi are a significant cause of peripheral embolization.
- Aortic thrombectomy combined with long-term anticoagulation is an effective treatment strategy.
Abstract:
With the advent of transesophageal echocardiography (TEE), giant thrombi of the descending aorta are becoming increasingly recognized as possible sources of peripheral emboli. This report describes the management of three patients presenting with multiple unexplained peripheral emboli. All three patients were treated successfully with aortic thrombectomy and long-term anticoagulation.
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