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Microencapsulation of oils using sodium alginate.

L W Chan¹, L T Lim, P W Heng

¹Department of Pharmacy, National University of Singapore, Singapore.

Journal of Microencapsulation

|November 4, 2000

Summary

Researchers explored encapsulating wheatgerm oil and evening primrose oil using sodium alginate. The emulsification method achieved high encapsulation efficiency for these oils, demonstrating its feasibility.

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Area of Science:

Materials Science
Chemical Engineering
Pharmaceutical Sciences

Background:

Wheatgerm oil and evening primrose oil are rich in beneficial fatty acids.
Encapsulation is crucial for stabilizing oils and improving their delivery.
Sodium alginate and calcium ions are commonly used for microencapsulation.

Purpose of the Study:

To investigate the feasibility of encapsulating wheatgerm oil and evening primrose oil using sodium alginate via emulsification.
To evaluate the impact of oil load on microsphere properties and encapsulation efficiency.
To determine the suitability of the developed method for fixed oils.

Main Methods:

Emulsification method using sodium alginate and calcium chloride.
Preparation of oil-in-water emulsions with varying oil loads.
Characterization of microspheres: physical appearance, oil content, encapsulation efficiency, flow properties, size distribution, and mean size.

Main Results:

Encapsulation efficiency and oil content increased with higher oil loads for wheatgerm oil.
Microsphere size increased significantly at 250% w/w oil load, with larger, spherical structures and more vesicles.
Similar encapsulation efficiencies were observed for evening primrose oil across different oil loads.
Maximum encapsulation efficiency of approximately 88% was achieved for wheatgerm oil.

Conclusions:

The emulsification method is feasible for encapsulating wheatgerm oil and evening primrose oil using sodium alginate.
Oil load significantly influences microsphere characteristics and encapsulation efficiency.
The developed method is effective for encapsulating fixed oils.

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