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Histocompatibility antigen (HLA) associations with multiple sclerosis in Iran
H Kalanie1, M Kamgooyan, H Sadeghian
1Department of Neurology, Shohada Hospital, Tajrish, Tehran, Iran.
Abstract:
Human leukocyte antigen (HLA) types were obtained from 79 Iranian patients with multiple sclerosis and compared with 100 controls. The prevalence of HLA-A24 (30.3% versus 18.0%), HLA-DR2 (43.0% versus 28. 0%) and HLA-DR15 (36.7% versus 23.0%) were significantly increased in multiple sclerosis patients compared with controls. However age at onset, and disease status (relapsing - remitting or primary progressive) did not show an association with any particular HLA type. Multiple Sclerosis (2000) 6 317 - 319
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