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Multifocal aggressive angiomyxoma: a case report.

A Kaur1, P S Makhija, E Vallikad

  • 1Department of Pathology, St Johns Medical College and Hospital, Bangalore, Karnataka, India.

Journal of Clinical Pathology
|November 7, 2000
PubMed
Summary
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This case report details aggressive angiomyxoma, a rare tumor, presenting as two distinct masses in a young woman. It highlights the importance of considering multifocal presentations for this gynecologic neoplasm.

Area of Science:

  • Gynecologic Oncology
  • Surgical Pathology
  • Vascular Tumors

Background:

  • Aggressive angiomyxoma is a rare mesenchymal tumor typically affecting the pelvic and perineal regions.
  • It predominantly occurs in adult women and is characterized by a high recurrence rate and potential for local invasion.

Observation:

  • A 25-year-old woman presented with urinary hesitancy and right iliac fossa pain.
  • Clinical examination revealed a left labial mass, initially suspected as a Bartholin gland cyst.
  • Pelvic ultrasound identified an additional mass in the right paravesical region.

Findings:

  • Surgical removal of two distinct masses, one from the left labium and the other from the right perivesical space.
  • Histopathological analysis of both masses revealed characteristic features of aggressive angiomyxoma: vascular channels within a myxoid stroma.

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  • This represents the first documented case of aggressive angiomyxoma presenting as multifocal, distinct masses in a single patient.

    • Implications:

    • This case underscores the necessity of comprehensive imaging and surgical exploration to identify all tumor foci in suspected aggressive angiomyxoma.
    • Recognizing multifocal presentation is crucial for accurate diagnosis and effective management of aggressive angiomyxoma.
    • Further research into the etiology and behavior of multifocal aggressive angiomyxoma is warranted.