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Updated: Aug 9, 2026

Comprehensive Evaluation of the Effectiveness and Safety of Placenta-Targeted Drug Delivery Using Three Complementary Methods
Published on: September 10, 2018
Cervical pregnancy treated with a single intravenous administration of methotrexate plus oral folinic acid
1Department of Obstetrics and Gynaecology, University of Queensland and Logan Hospital, Australia.
Abstract:
Cervical pregnancy is a rare form of ectopic pregnancy and at present there is no consensus as to the most appropriate treatment. A patient with a 6-week cervical pregnancy was successfully treated with a single intravenous administration of methotrexate and oral folinic acid without any adjuvant therapy Her recovery was uncomplicated. She subsequently conceived and was delivered by Caesarean section of a live healthy male baby. The efficacy of the described regimen in the management of a cervical pregnancy requires further assessment. This modality of treatment does not appear to adversely affect fertility and future pregnancies.
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