Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Kinematic coordinates in which motor cortical cells encode movement direction.

R Ajemian1, D Bullock, S Grossberg

  • 1Department of Cognitive and Neural Systems and Center for Adaptive Systems, Boston University, Boston, Massachusetts 02215, USA.

Journal of Neurophysiology
|November 9, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of white matter tracts between and within the dorsal and ventral streams.

Brain structure & function·2022
Same author

Visual Information Routes in the Posterior Dorsal and Ventral Face Network Studied with Intracranial Neurophysiology and White Matter Tract Endpoints.

Cerebral cortex (New York, N.Y. : 1991)·2021
Same author

Measurement of <math></math> production with the hadronically decaying boson reconstructed as one or two jets in <i>pp</i> collisions at <math> </math> with ATLAS, and constraints on anomalous gauge couplings.

The European physical journal. C, Particles and fields·2020
Same author

Study of <math></math> and <math></math> production in <math></math> collisions at <math> </math> and search for anomalous quartic gauge couplings with the ATLAS experiment.

The European physical journal. C, Particles and fields·2020
Same author

Identification and rejection of pile-up jets at high pseudorapidity with the ATLAS detector.

The European physical journal. C, Particles and fields·2020
Same author

Measurement of detector-corrected observables sensitive to the anomalous production of events with jets and large missing transverse momentum in <math></math> collisions at <math> </math>  TeV using the ATLAS detector.

The European physical journal. C, Particles and fields·2020
Same journal

Deep Learning Reveals Cross-Modal Neural Representations of Auditory and Visual Mental Imagery in MEG.

Journal of neurophysiology·2026
Same journal

Speech sensorimotor adaptation in young adult cochlear implant users with early implantation.

Journal of neurophysiology·2026
Same journal

How Visual Context Influences Lateral Stepping Regulation While Walking on Winding Paths.

Journal of neurophysiology·2026
Same journal

Simultaneous neuron evidence for much higher covariation with saccadic reaction time of superior colliculus than primary visual cortex visual responses.

Journal of neurophysiology·2026
Same journal

Separate Dorsolateral Prefrontal Cortex Regions Participate in Distinct Large-Scale Networks Differentially Recruited for Social and Cognitive Control Functions.

Journal of neurophysiology·2026
Same journal

Comprehensive Analysis of Auditory Nerve Fiber Responses using Fiber-Specific Modeling.

Journal of neurophysiology·2026
See all related articles

Researchers explored how the brain encodes movement direction using a mathematical framework. They found that joint angle coordinates best explain cellular responses during reaching tasks, aiding future experimental designs.

Area of Science:

  • Neuroscience
  • Motor Control
  • Computational Neuroscience

Background:

  • Goal-directed reaching involves complex sensorimotor transformations generating muscle activation patterns.
  • A key question in motor cortex research is identifying the coordinate systems used by neurons to encode movement direction.

Purpose of the Study:

  • To develop a mathematical framework for calculating cellular preferred directions across different coordinate systems.
  • To compare the empirical adequacy of Cartesian spatial, shoulder-centered, and joint angle coordinate systems for primary motor cortex (MI) cells.

Main Methods:

  • A mathematical framework was developed to compute spatial preferred directions (pds) as a function of hypothesized coordinate systems.
  • Three coordinate systems were explicitly modeled: Cartesian spatial, shoulder-centered, and joint angle.

Related Experiment Videos

  • The framework was used to analyze cellular responses during a curved motion experiment.

    • Main Results:

    • Computed patterns of spatial pds differed distinctly across the three modeled coordinate systems.
    • The joint angle coordinate system provided the best explanation for observed cellular response properties in the curved motion experiment.
    • The developed framework can guide the design of experiments to differentiate between coordinate system hypotheses.

    Conclusions:

    • The study provides a novel mathematical framework to investigate neural encoding of movement direction.
    • Evidence suggests that joint angle coordinates are a strong candidate for how primary motor cortex cells represent movement.
    • The framework facilitates the design of targeted experiments to resolve ambiguities in neural coding hypotheses.