Related Experiment Videos
[Split-course radiotherapy or treatment interruption]
1Klinik für Radioonkologie-Strahlentherapie Klinikum Fulda. hjfeldmann.raz@klinikum-fulda.de
Background:
Experimental and clinical studies have shown that a prolonged overall treatment time is associated with a decrease in local tumor control.
Methods:
In a brief review, the clinical data of radiotherapy with split-course or treatment interruption were collected.
Results And Conclusion:
There was a detrimental effect of the treatment interruption on overall or disease-specific survival in patients with locally advanced head and neck cancer or non-small-cell lung cancer in particular in patients with good prognostic factors and well to moderate differentiated tumors. Therefore, interruption of radiotherapy in patients with curative treatment should be avoided.