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Metabolic control: a new solution to an old problem
1Wellcome Trust Biocentre, School of Life Sciences, University of Dundee, Scotland, UK. d.g.hardie@dundee.ac.uk
Current Biology : CB
|November 9, 2000
Abstract:
The phenomenon whereby the presence of oxygen regulates the rate of glucose metabolism was first described by Louis Pasteur. A novel mechanism has now been discovered, involving the AMP-activated protein kinase cascade, that can account for the Pasteur effect in ischaemic heart muscle.