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An exploratory study of ethnicity and psychotherapy outcome among HIV-positive patients with depressive symptoms
J C Markowitz1, L A Spielman, M Sullivan
1Department of Psychiatry, Weill Medical College of Cornell University, New York, New York 10021, USA. jcmarko@mail.med.cornell.edu
Abstract:
Few data address the relationship between ethnic status and psychotherapy outcome. This study reports data from a four-cell, 16-week controlled clinical trial for HIV-positive patients with depressive symptoms. Patients (N = 101) were randomized to 16 weeks of treatment with interpersonal psychotherapy, cognitive-behavioral therapy (CBT), supportive psychotherapy, or imipramine plus supportive psychotherapy. Analyses found an ethnicity-by-treatment interaction wherein African-American subjects (n = 18) assigned to CBT (n = 4) had significantly poorer outcomes than other patients. This is the first study to uncover an ethnicity-by-specific psychotherapy interaction. Its meaning is unclear. This charged topic requires cautious treatment, particularly given the small sample size in this study, but warrants further research.
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