Clinical applications of the continuous flow blood separator machine

Area of Science:

• Biomedical Engineering
• Immunology
• Hematology

Background:

• Continuous flow blood separation technology offers precise control over blood component manipulation.
• Clinical immunology requires methods for selective removal or collection of specific blood fractions.

Purpose of the Study:

• To evaluate the NCl/IBM Continuous Flow Blood Separator for selective blood component removal and exchange.
• To explore its applications in clinical immunology and therapeutic interventions.

Main Methods:

• Utilized the NCl/IBM Continuous Flow Blood Separator for apheresis procedures.
• Demonstrated selective removal of packed red blood cells, leucocyte-rich/platelet-rich layers, and plasma.
• Collected abnormal fractions for disposal and normal constituents for therapeutic use.

Main Results:

• The apparatus proved safe and effective for selective removal and exchange of blood components.
• Successful harvesting of immune leucocytes for transfer factor preparation was achieved.
• Demonstrated efficacy in removing cryo- or macro-globulins, immune complexes, and blocking factors.

Conclusions:

• The NCl/IBM Continuous Flow Blood Separator is a versatile tool for clinical immunology.
• It enables therapeutic applications such as component replacement and immune cell harvesting.
• Further investigation into medical problems encountered during its use is warranted.