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Updated: Oct 10, 2026

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)
Published on: September 14, 2010
Human herpesvirus-8 infection among heterosexual partners of patients with classical Kaposi's sarcoma
L Brambilla1, V Boneschi, S Ferrucci
1Istituto di Dermatologia, IRCCS Ospedale Maggiore, Via Pace 9, 20122 Milan, Italy.
Background:
DNA sequences of human herpesvirus-8 (HHV8) are found in lesions of Kaposi's sarcoma (KS).
Objectives:
To verify the hypothesis of the sexual transmission of HHV8 infection.
Methods:
We used the immunoperoxidase assay to study the prevalence of serum antibodies to HHV8-related antigens in 27 consorts of patients with classical KS, and in a control group of 25 healthy women.
Results:
Forty-four per cent of the study group were positive, compared with 8% of the controls.
Conclusions:
The sexual route may be one of the possible ways of transmission of the HHV8 virus.
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