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Updated: Jul 16, 2026

Chemotherapy-induced Vascular Toxicity - Real-time In vivo Imaging of Vessel Impairment
Published on: January 7, 2015
Calciphylaxis in a patient without renal failure or elevated parathyroid hormone: possible aetiological role of
S Goyal1, K M Huhn, T T Provost
1Department of Dermatology, The Johns Hopkins University, School of Medicine, 601 North Caroline Street, Baltimore, MD 21287-0900, USA.
Abstract:
Calciphylaxis is a rare, often fatal disease characterized clinically by progressive cutaneous necrosis and ulceration, and histologically by vascular calcification and thrombosis. It has been described in association with end-stage renal disease, after initiation of dialysis, following renal transplantation, and in patients with hyperparathyroidism. We present the first case of calciphylaxis occurring in a patient with both normal renal function and parathyroid hormone level and discuss the possible aetiological role of chemotherapy-induced functional protein C and protein S deficiency.
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