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Isoniazid (I.N.H.) in the treatment of depressive syndrome: a pilot trial
Abstract:
An account of a pilot trial of Isoniazid as an anti-depressant is given. About 70% of the total patients improved and above 50% of them improved markedly. The improvement was sustained even after withdrawal of the drug. No patient worsened and the drug was very well tolerated on the whole. These preliminary results of a pilot trial amply justifies further exhaustive study of this drug, particularly in depressions.