Jove
Visualize
Contact Us

Related Experiment Videos

Molecular and reconstructive urology: a coming together.

R A Gardiner1

  • 1Department of Surgery, University of Queensland, Royal Brisbane Hospital, Herston, Australia. f.gardiner@mailbox.uq.edu.au

World Journal of Surgery
|November 9, 2000
PubMed
Summary

Advances in prostate-specific antigen (PSA) testing enable earlier prostate cancer diagnosis, leading to improved surgical techniques. Ongoing molecular research aims to enhance reconstructive urologic surgery and patient outcomes beyond the year 2000.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Men's help-seeking in the first year after diagnosis of localised prostate cancer.

European journal of cancer care·2016
Same author

The global burden of major infectious complications following prostate biopsy.

Epidemiology and infection·2015
Same author

Financial toxicity: a potential side effect of prostate cancer treatment among Australian men.

European journal of cancer care·2015
Same author

Prevalence and predictors of cancer specific distress in men with a family history of prostate cancer.

Psycho-oncology·2013
Same author

Intervening to improve psychological outcomes for men with prostate cancer.

Psycho-oncology·2012
Same author

ProsCan for Couples: a feasibility study for evaluating peer support within a controlled research design.

Psycho-oncology·2011
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Urology
  • Molecular Biology
  • Surgical Innovation

Background:

  • Prostate-specific antigen (PSA) testing has improved early prostate cancer detection, increasing radical prostatectomies.
  • This shift in surgical practice has enhanced understanding of sphincter anatomy and preservation techniques.
  • Consequently, orthotopic urinary diversion for invasive bladder cancer has gained popularity.

Purpose of the Study:

  • To discuss molecular and basic science research addressing limitations of the PSA/transrectal ultrasonographic biopsy approach.
  • To present advancements in reconstructive urologic surgery.
  • To explore future patient benefits from molecular and basic science developments.

Main Methods:

  • Development of a bladder acellular matrix graft for urothelial regeneration.

Related Experiment Videos

  • Engineering of a simplified and more durable bowel continence mechanism.
  • Experimental renal preservation techniques separating urine production and direction roles.

    • Main Results:

    • A bladder acellular matrix graft shows potential as a regenerative scaffold.
    • A novel bowel continence mechanism is being developed for improved durability.
    • A new experimental technique for renal preservation is proposed.

    Conclusions:

    • Molecular and basic science research are crucial for overcoming diagnostic limitations.
    • These advancements promise to drive further reconstructive surgical innovations.
    • Future developments aim to translate basic science discoveries into significant patient benefits in urologic surgery.