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Cervical cancer screening in Sweden
1Karolinska Institutet, Microbiology and Tumour Biology Centre (MTC), PO Box 280, S-171 77, Stockholm, Sweden. joadil@mbox.ki.se
Summary
Organized cervical cancer screening in Sweden has significantly reduced squamous cell carcinoma incidence. However, adenocarcinoma rates have risen, prompting quality improvements and HPV infection screening evaluations.
Area of Science:
- Oncology
- Public Health
- Epidemiology
Background:
- Sweden implemented organized cervical cancer screening in the mid-1960s.
- Cervical cancer incidence has markedly declined since screening began.
- While squamous cell carcinoma decreased by 60%, adenocarcinoma rates have increased.
Purpose of the Study:
- To review cervical cancer screening practices in Sweden.
- To discuss current quality improvement efforts in the screening program.
- To examine ongoing randomized evaluations of primary human papillomavirus (HPV) infection screening.
Main Methods:
- Analysis of historical cervical cancer incidence data in Sweden.
- Review of current screening guidelines and quality improvement initiatives.
- Overview of ongoing randomized trials for HPV primary screening.
Main Results:
- Significant reduction in squamous cell carcinoma incidence attributed to organized screening.
- An observed increase in adenocarcinoma incidence.
- Approximately 950,000 Papanicolaou (Pap) smears are taken annually, with 31% within the organized program.
Conclusions:
- Organized cervical cancer screening has been effective in reducing overall incidence, particularly squamous cell carcinoma.
- The rise in adenocarcinoma warrants further investigation and potential adjustments to screening strategies.
- Ongoing evaluations of HPV primary screening aim to enhance the effectiveness and quality of cervical cancer prevention.