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Swyer-James-MacLeod syndrome.

P W Chan1, J A DeBruyne, A Y Goh

  • 1Department of Paediatrics, University Malaya Medical Centre, Kuala Lumpur.

The Medical Journal of Malaysia
|November 10, 2000
PubMed
Summary

Swyer-James-MacLeod syndrome, a rare childhood lung disorder, presents with chronic cough and wheezing. Diagnosis involves identifying unilateral lung volume loss, reduced vascularity, and decreased perfusion on imaging scans.

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Area of Science:

  • Pediatric Pulmonology
  • Radiology
  • Nuclear Medicine

Background:

  • Swyer-James-MacLeod syndrome is a rare sequela of childhood respiratory infections.
  • It characteristically affects lung development and function unilaterally.

Observation:

  • This report details two pediatric cases presenting with chronic cough and recurrent wheezing.
  • Both patients met the diagnostic criteria for Swyer-James-MacLeod syndrome.

Findings:

  • Diagnostic confirmation included unilateral hyperlucency and volume loss on chest X-ray.
  • CT scans revealed unilateral reduction in pulmonary vascularity.
  • Technetium-99m lung scans demonstrated unilateral loss of perfusion.

Implications:

  • Early and accurate diagnosis of Swyer-James-MacLeod syndrome is crucial for appropriate management.
  • Radiological and nuclear medicine imaging are essential for confirming the diagnosis.
  • Understanding these imaging findings aids in differentiating this rare condition from other causes of chronic respiratory symptoms in children.

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