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Toxin Induction and Protein Extraction from Fusarium spp. Cultures for Proteomic Studies
Published on: February 16, 2010
A short stereoselective total synthesis of the fusarium toxin equisetin
L T Burke1, D J Dixon, S V Ley
1Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.
Organic Letters
|November 14, 2000
Abstract:
A short stereoselective synthesis of the fusarium toxin equisetin, an N-methylserine-derived acyl tetramic acid and potent inhibitor of HIV-1 integrase enzyme, is described using as the key step a stereoselective lithium perchlorate mediated intramolecular Diels-Alder reaction of a fully conjugated E,E,E-triene with a trisubstituted gamma,delta-unsaturated beta-ketothioester.

