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Autoimmune progesterone urticaria
C Vasconcelos1, P Xavier, A P Vieira
1Department of Dermatology and Venereology, University Hospital of São João, Porto, Portugal.
Abstract:
Autoimmune progesterone dermatitis is a rare cutaneous disorder characterized by recurrent and cyclic skin eruption with variable morphology, occurring during the luteal phase. A case of autoimmune progesterone urticaria in a 47-year-old woman is reported. An intradermal progestin test revealed a strong reactivity against this hormone. Treatment with tamoxifen and leuprolide acetate induced only a partial remission of urticaria. Bilateral oophorectomy was performed with absolute clearing of cutaneous lesions.