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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Published on: June 2, 2014

Fever: a novelty among the symptoms accompanying migraine attacks in children

D Lendvai1, P Verdecchia, R Crenca

  • 1Department of Pediatrics, University La Sapienza, Rome, Italy.

European Review for Medical and Pharmacological Sciences
|November 15, 2000
PubMed

Insights

This study analyzed 1787 children with headaches, finding primary headache common. Fever accompanied migraine in 9% of cases, suggesting potential links to neurotransmitter disregulation.

Area of Science:

  • Pediatric Neurology
  • Clinical Medicine

Background:

  • Headache is a frequent syndrome in early childhood.
  • Understanding the etiopathogenesis of pediatric headache is crucial for accurate diagnosis and management.

Purpose of the Study:

  • To analyze the clinical characteristics of headaches in a pediatric population.
  • To investigate the prevalence and associated symptoms of primary headache in children.
  • To explore the occurrence of fever in conjunction with migraine.

Main Methods:

  • A retrospective analysis of 1787 children (aged 3-14 years) diagnosed with headache.
  • Detailed anamnesis, physical examinations, and diagnostic tests including blood work, urinalysis, imaging (X-rays, scans), and vision tests.
  • Symptom documentation, focusing on associated features like photophobia, pallor, nausea, vomiting, movement intolerance, and fever.

Main Results:

  • 1724 children (96.5%) were diagnosed with primary headache.
  • Common accompanying symptoms included phonophobia/photophobia (47%), pallor (43%), nausea (41%), movement intolerance (40%), and vomiting (31%).
  • Fever was present in 156 children (9%) with migraine.

Conclusions:

  • Primary headache is highly prevalent in the studied pediatric cohort.
  • Fever associated with migraine in children warrants further investigation.
  • Current hypotheses suggest neurotransmitter disregulation (serotonin, catecholamines, prostaglandins) underlies headache mechanisms.

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