Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Frequency-dependent responses exhibited by multiple regions in human auditory cortex.

T M Talavage1, P J Ledden, R R Benson

  • 1Speech and Hearing Sciences Program, MIT-Harvard Division of Health Sciences and Technology, Cambridge, MA, USA. tmt@ecn.purdue.edu

Hearing Research
|November 15, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of CBF Measured with Combined Velocity-Selective Arterial Spin-Labeling and Pulsed Arterial Spin-Labeling to Blood Flow Patterns Assessed by Conventional Angiography in Pediatric Moyamoya.

AJNR. American journal of neuroradiology·2019
Same author

Diagnostic Performance of a 10-Minute Gadolinium-Enhanced Brain MRI Protocol Compared with the Standard Clinical Protocol for Detection of Intracranial Enhancing Lesions.

AJNR. American journal of neuroradiology·2017
Same author

Cyclic Vomiting Syndrome is characterized by altered functional brain connectivity of the insular cortex: A cross-comparison with migraine and healthy adults.

Neurogastroenterology and motility·2016
Same author

The imagined itch: brain circuitry supporting nocebo-induced itch in atopic dermatitis patients.

Allergy·2015
Same author

Repeatability of Standardized and Normalized Relative CBV in Patients with Newly Diagnosed Glioblastoma.

AJNR. American journal of neuroradiology·2015
Same author

DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts.

Developmental neuropsychology·2015
Same journal

TGF-β signaling regulates flat epithelium formation in severely injured adult mouse utricle through epithelial-mesenchymal transition.

Hearing research·2026
Same journal

Membrane scaffolding in auditory hair cells - a molecular tightrope walk enables lateral wall stiffness and flexibility.

Hearing research·2026
Same journal

Speech-in-noise recognition during hearing protector use: Human performance and acoustic prediction.

Hearing research·2026
Same journal

Estimation of hair cell loss from audiograms.

Hearing research·2026
Same journal

Cochlear size variation in a large-scale international multicentre cohort.

Hearing research·2026
Same journal

Estimation of minor-to-moderate conductive hearing loss with distortion-product otoacoustic emissions in humans.

Hearing research·2026
See all related articles

Human auditory cortex tonotopy reveals more frequency-organized areas than previously known. Functional magnetic resonance imaging identified eight distinct frequency-dependent response regions in the superior temporal lobe.

Area of Science:

  • Neuroscience
  • Auditory Neuroscience
  • Human Neuroimaging

Background:

  • Animal studies reveal detailed tonotopic organization in the auditory cortex with multiple tonotopic maps.
  • Knowledge of tonotopy in the human auditory cortex is limited, with uncertainty regarding the number and location of maps.

Purpose of the Study:

  • To investigate and map the tonotopic organization of the human auditory cortex.
  • To identify and characterize frequency-sensitive regions within the human auditory cortex.
  • To propose a correspondence between identified regions and anatomically defined cortical areas.

Main Methods:

  • Utilized functional magnetic resonance imaging (fMRI) for non-invasive neural activity localization in humans.
  • Subjects listened to alternating low- (below 660 Hz) and high- (above 2490 Hz) frequency stimuli.

Related Experiment Videos

  • Identified frequency-dependent response regions (FDRRs) based on differential responses to spectral content.

    • Main Results:

    • Multiple regions in the superior temporal lobe showed frequency-dependent responses.
    • Eight distinct FDRRs were consistently identified across subjects.
    • Four FDRRs responded more to higher frequencies, and four responded more to lower frequencies.

    Conclusions:

    • The human auditory cortex contains a greater number of tonotopically organized areas than previously recognized.
    • Findings suggest at least four or more tonotopic areas in the human auditory cortex.
    • A proposed correspondence links the identified FDRRs to specific anatomical areas on the superior temporal lobe.