Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prognostic implication of contralateral secondary electrographic seizures in temporal lobe epilepsy.

K H Lee1, Y D Park, D W King

  • 1Department of Neurology, Department of Neurosurgery, Medical College of Georgia, Augusta, GA 30912, USA.

Epilepsia
|November 15, 2000
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Subtotal colectomy and ileorectal anastomosis for slow transit constipation: clinical follow-up at median of 15 years.

Techniques in coloproctology·2020
Same author

A Long Short-Term Memory neural network for the detection of epileptiform spikes and high frequency oscillations.

Scientific reports·2019
Same author

Pannexin-2 is expressed in the human colon with extensive localization in the enteric nervous system.

Neurogastroenterology and motility·2015
Same author

The Wada test in the evaluation for epilepsy surgery.

Neurosciences (Riyadh, Saudi Arabia)·2013
Same author

Pre-surgical evaluation for epilepsy surgery.

Neurosciences (Riyadh, Saudi Arabia)·2013
Same author

Antiepileptic drug clearance and seizure frequency during pregnancy in women with epilepsy.

Epilepsy & behavior : E&B·2013

Distinct secondary electrographic seizures (DSES) spreading to the opposite temporal lobe in epilepsy patients predict a poorer outcome after surgery. This pattern is also linked to more frequent bitemporal seizures.

Area of Science:

  • Neurology
  • Epileptology
  • Clinical Neurophysiology

Background:

  • Interhemispheric seizure propagation is common in temporal lobe epilepsy (TLE).
  • The prognostic significance of distinct secondary electrographic seizures (DSES) originating in the contralateral temporal lobe remains unclear.

Purpose of the Study:

  • To investigate whether DSES in TLE is an indicator of unfavorable surgical outcomes.
  • To determine the association between DSES and bitemporal seizure activity.

Main Methods:

  • Retrospective review of intracranial EEG recordings, 1-year outcomes, and medical records from 51 patients undergoing anterior temporal lobectomy.
  • Definition of DSES: seizure spreading to the contralateral temporal lobe with distinct, independently evolving EEG features in focal contacts.

Related Experiment Videos

  • DSES was considered predominant if it occurred in over 50% of recorded seizures.

    • Main Results:

    • Patients with predominant DSES had significantly lower 1-year seizure-free rates (47%) compared to those without (84%) (p < 0.01).
    • Predominant DSES was strongly associated with bitemporal independent seizures (9/19 vs. 0/32, p < 0.001).

    Conclusions:

    • Distinct contralateral secondary electrographic seizures are a predictor of unfavorable surgical outcomes in TLE.
    • The presence of DSES is associated with a higher likelihood of bitemporal seizure patterns.