[BCG-septicemia and mucocutaneous candidiasis due to familial combined immunodeficiency (authors transl)]
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A rare combined immunodeficiency caused mucocutaneous candidiasis and BCG-septicemia in an infant. Early immunological diagnosis is crucial for infants with severe infections, and live vaccines are contraindicated.
Area of Science:
- Immunology
- Pediatrics
- Infectious Diseases
Abstract:
The history of a patient with mucocutaneous candidiasis and BCG-septicemia is reported. Combined immunodeficiency has been diagnosed as the underlying cause. A sister of the patient died at seven months of age under similar circumstances. The importance of the immunological diagnosis in severe bacterial and mycotic infection during early infancy has been emphasized. In such cases vaccinations with life vaccine are strongly contraindicated.