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Predictors of conversion to sinus rhythm using ibutilide for atrial fibrillation or flutter
1Texas Heart Institute at St. Luke's Episcopal Hospital, and Baylor College of Medicine, Houston, USA.
The American Journal of Cardiology
|November 15, 2000
Summary
Recent onset of atrial fibrillation or flutter, atrial flutter rhythm, no heart failure history, and no digoxin use predict successful ibutilide conversion to sinus rhythm.
Area of Science:
- Cardiology
- Clinical Electrophysiology
Background:
- Atrial fibrillation and atrial flutter are common arrhythmias.
- Ibutilide is an antiarrhythmic medication used for cardioversion.
Purpose of the Study:
- To identify predictors of successful conversion to sinus rhythm using ibutilide.
- To analyze factors influencing treatment outcomes for atrial arrhythmias.
Main Methods:
- Retrospective study of 201 consecutive patients treated with ibutilide.
- Multivariate analysis to identify significant predictive factors for conversion.
Main Results:
- Recent onset of arrhythmia was associated with successful conversion.
- Underlying atrial flutter rhythm predicted successful cardioversion.
- Absence of congestive heart failure history improved conversion rates.
- Lack of concomitant digoxin therapy was linked to better outcomes.
Conclusions:
- Predictors for successful ibutilide cardioversion include recent onset, atrial flutter, no heart failure history, and no digoxin use.
- These factors can help guide treatment decisions for patients with atrial fibrillation or flutter.
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