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Coronary stent implantation in diabetic versus nondiabetic patients. Early and late outcomes
D M Bayerl1, E Siqueira, I Moscoso
1Hospital São Joaquim da Real e Benemérita Sociedade Portuguesa de Beneficência, São Paulo, SP, Brazil.
Insights
Coronary stenting is effective for diabetic patients, showing similar success rates to non-diabetics. However, diabetics experienced more in-hospital heart attacks and required more revascularization procedures.
Area of Science:
- Cardiology
- Interventional Cardiology
- Diabetology
Background:
- Coronary heart disease (CHD) affects both diabetic and non-diabetic populations.
- Coronary stenting is a common intervention for CHD.
- Assessing outcomes in diabetic patients undergoing stenting is crucial for personalized treatment.
Purpose of the Study:
- To compare in-hospital results and clinical outcomes of coronary stenting between diabetic and non-diabetic patients.
- To evaluate the efficacy and safety of coronary stent implantation in patients with and without diabetes.
Main Methods:
- Retrospective analysis of 386 patients with CHD undergoing coronary stent implantation from July 1997 to April 1999.
- Patients were divided into diabetic (n=81) and non-diabetic (n=305) groups.
- Comparison of in-hospital complications and long-term clinical evolution.
Main Results:
- Similar angiographic success rates were observed: 96.6% in diabetics vs. 97.9% in non-diabetics (p=ns).
- Diabetic patients had a significantly higher rate of in-hospital myocardial infarction (7.4% vs. 1.9%, p=0.022).
- Follow-up showed similar rates of asymptomatic patients, myocardial infarction, and death, but a greater need for revascularization in diabetics (15% vs. 2.4%, p<0.001).
Conclusions:
- Coronary stenting is an efficient procedure for diabetic patients, yielding high angiographic and clinical success rates comparable to non-diabetics.
- Diabetic patients undergoing coronary stenting face increased risks of in-hospital myocardial infarction and a higher likelihood of requiring repeat revascularization.
Objective:
To assess whether coronary stenting in diabetic patients provides in-hospital results and clinical evolution similar to those in nondiabetic patients.
Methods:
From July '97 to April '99 we performed coronary stent implantation in 386 patients with coronary heart disease, who were divided into two groups: diabetic patients and nondiabetic patients. The in-hospital results and the clinical evolution of each group were retrospectively analyzed.
Results:
The nondiabetic group comprised 305 (79%) patients and the diabetic group 81 (21%) patients. Basic clinical and angiographic characteristics were similar. Angiographic success was in diabetics = 96.6% vs in nondiabetics = 97.9% (p=ns). Among the major complications in the in-hospital phase, the rate of myocardial infarction was higher in the diabetic group (7.4% vs 1.9%) (p=0.022). In the follow-up, a favorable and homogeneous evolution occurred in regard to asymptomatic patients, myocardial infarction, and death in the groups. A greater need for revascularization, however, existed in the diabetic patients (15% vs 2.4%, p<0.001).
Conclusion:
Coronary stenting in diabetic patients is an efficient procedure, with a high angiographic and clinical success rate similar to that in nondiabetic patients. Diabetic patients, however, had a higher incidence of in-hospital myocardial infarction and a greater need for additional myocardial revascularization.
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