Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Assessment of explanted PTCA balloons.

D Behrend1, G Zinner, K Sternberg

  • 1University of Rostock, Institute of Biomedical Engineering, Germany.

Journal of Biomaterials Applications
|November 18, 2000
PubMed
Summary

This study investigated explanted percutaneous transluminal coronary angioplasty (PTCA) catheters, revealing adherent protein layers and embedded plaque particles on all deployed devices. Water-insoluble proteins were detected, highlighting potential risks associated with catheter re-use.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "The overlooked effects of environmental impacts on root:shoot ratio in experiments and soil-crop models" [Sci. Total Environ. 955 (2024) 176738].

The Science of the total environment·2026
Same author

The overlooked effects of environmental impacts on root:shoot ratio in experiments and soil-crop models.

The Science of the total environment·2024
Same author

Reliability and accuracy of straightforward measurements for liver volume determination in ultrasound and computed tomography compared to real volumetry.

Scientific reports·2022
Same author

Blood product wastage reduction by utilising low-cost, low-impact multimodal physician-to-physician communication initiatives.

Transfusion medicine (Oxford, England)·2019
Same author

Cetuximab, fluorouracil and cisplatin with or without docetaxel for patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck (CeFCiD): an open-label phase II randomised trial (AIO/IAG-KHT trial 1108).

European journal of cancer (Oxford, England : 1990)·2019
Same author

Association Between Vitamin D and Adrenal Parameters with Metabolic and Inflammatory Markers in Polycystic Ovary Syndrome.

Scientific reports·2019

Area of Science:

  • Biomaterials Science
  • Medical Device Analysis
  • Cardiovascular Technology

Background:

  • Percutaneous transluminal coronary angioplasty (PTCA) involves using balloon catheters.
  • Catheter re-use is a concern due to potential surface contamination.
  • Understanding the surface properties of explanted catheters is crucial.

Purpose of the Study:

  • To characterize the surface of explanted PTCA balloon catheters.
  • To identify adhered substances, including proteins and plaque particles.
  • To evaluate the impact of angioplasty on catheter surface integrity.

Main Methods:

  • Examination of 168 explanted PTCA balloon catheters from six types and three manufacturers.
  • Utilized light microscopy, scanning electron microscopy (SEM), X-ray microanalysis, and FT-IR-ATR spectroscopy.

Related Experiment Videos

  • Employed silver staining and Lowry analysis for protein detection.

    • Main Results:

    • All deployed PTCA catheters showed adherent protein layers and embedded plaque particles.
    • SEM revealed fissuring and micro-tearing on balloon surfaces.
    • Lowry analysis confirmed the presence of water-insoluble proteins (average 17 microg/ml), while silver staining and FT-IR-ATR did not detect proteins.

    Conclusions:

    • Explanted PTCA catheters are consistently coated with adherent, water-insoluble proteins and debris.
    • Surface damage, including micro-tearing, is evident after deployment.
    • These findings underscore the risks associated with PTCA catheter re-use.