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Optimization of homogenization conditions used to isolate mRNAs in processes of myelinating oligodendrocytes

R M Gould1, C M Freund, J Engler

  • 1N. Y. S. Institute for Basic Research in Developmental Disabilities, Staten Island, USA.

The Biological Bulletin
|November 18, 2000
PubMed
Abstract

No abstract available in PubMed .

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Tissue homogenization involves disintegrating tissue architecture and lysing cells, and is an early step in isolating and analyzing cellular components. The method used for homogenization depends on the sample type, the amount of sample available, the analyte to be obtained, and the sensitivity of the method. These methods are broadly classified as mechanical and non-mechanical methods.
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