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Restoration of immunity with interleukin-2 therapy

K A Smith1, E L Jacobson, R Emert

  • 1Department of Medicine, Weill Medical College of Cornell University, New York, USA.

The AIDS Reader
|November 18, 2000
PubMed

HIV replication can now be effectively suppressed using antiretroviral combination regimens. The search continues, however, for ways to restore the immune response and eliminate reservoirs of latent infection. Interleukin-2 (IL-2) may augment the immune response in HIV-infected persons. This article discusses the rationale for using IL-2 in those with HIV disease and reviews key trials of IL-2 treatment regimens.

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