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Restoration of immunity with interleukin-2 therapy
K A Smith1, E L Jacobson, R Emert
1Department of Medicine, Weill Medical College of Cornell University, New York, USA.
The AIDS Reader
|November 18, 2000
Abstract:
HIV replication can now be effectively suppressed using antiretroviral combination regimens. The search continues, however, for ways to restore the immune response and eliminate reservoirs of latent infection. Interleukin-2 (IL-2) may augment the immune response in HIV-infected persons. This article discusses the rationale for using IL-2 in those with HIV disease and reviews key trials of IL-2 treatment regimens.