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Distinguishing withdrawal relief from absolute facilitation: commentary on Bell et al

W S Pritchard1, J H Robinson

  • 1Psychophysiology Laboratory, R. J. Reynolds Tobacco Company, Winston-Salem, North Carolina 27102, USA. pritchw@rjrt.com

Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco
|November 18, 2000
PubMed

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Overview
Ethers can be prepared from organic compounds by various methods. Some of them are discussed below,
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In this method, in the presence of protic acids, alcohol dehydrates to produce alkenes and ethers under different conditions. For example, in the presence of sulphuric acid, dehydration of ethanol at 413 K yields ethoxyethane, whereas it yields ethene at 443 K.
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The acid-catalyzed addition of alcohol to an alkene involves treating the alkene with an excess of alcohol in the presence of an acid catalyst to form an ether under suitable conditions. The hydrogen will add to the less substituted carbon so that the nucleophile can attack the more substituted...
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