[Effectiveness of immunoprophylaxis in negative Rhesus factor]

In the research an evaluation was made of the effectiveness of immunoprophylaxis applied in fetomaternal incompatibility in the range of antigen D. Material was based on patients who were delivered in the Clinic of Obstetrics and Gynaecology, Medical Academy in Bydgoszcz in the years 1981-1999. In that period of time there were 46,398 deliveries. 6217 pregnancies were found to be serologically incompatible in the range of antigen D. In 5384 patients immunoglobulin anti D was administered at a dose of 15-300 micrograms. At one time 311 patients with serological conflict in the range of antigen D were treated. Postpartum immunoprophylaxis was found effective in 93.9%. Lak of compliance with the principles of immunoprophylaxis, especially in patients after a miscarriage, and too low doses of Ig anti D were recognised as the reasons for incomplete effectiveness.