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[Glutathione peroxidase concentration in the peritoneal fluid from infertile women]
G Polak1, M Kozioł-Montewka, R Tarkowski
1Katedry i Zakładu Mikrobiologii Lekarskiej AM w Lublinie.
Objectives:
To assess the concentration of Plasma Glutathione Peroxidase (plGPx) in the peritoneal fluid (PF) of patients with unexplained infertility and infertile women with minimal and mild endometriosis.
Materials And Methods:
33 women were studied, including 8 infertile women with minimal or mild endometriosis, 15 patients with unexplained infertility and 10 patients with tubal occlusion (a reference group). Concentration of plGPx was measured in the PF using a commercially available ELISA kit (Oxis Inc.).
Results:
The plGPx concentration was significantly (p = 0.04) lower in PF from women with unexplained infertility (846 +/- 177 ng/ml) compared to the reference group (1023 +/- 238 ng/ml), but did not differ significantly (p = 0.25) between women with endometriosis (918 +/- 81 ng/ml) and patients with tubal infertility.
Conclusions:
Our results suggest that low peritoneal plGPx concentration may play a role in the pathogenesis of infertility.