Long-term complications of living donor liver transplantation

1. Donor outcome after living donor liver transplantation (LDLT) is related to type of liver resection. Left lateral segmentectomy is used in pediatric cases and right lobectomy is used in adult cases. 2. Biliary complications occur in 5% to 10% of both pediatric and adult cases. 3. Three donors, 2 in pediatric LDLT and 1 in adult LDLT, have died. Estimated mortality is 0.13% for pediatric donation and 0.2% for adult donation. 4. Postoperative cholestasis occurs commonly in donors, but clinically relevant jaundice occurs in less than 5%. 5. Other donor morbidity may be related to incisional hernias, postoperative gastric dysfunction, and pain. 6. Donors report overall satisfaction with LDLT, and 88% believed that the role of LDLT should be increased. 7. All donors returned to predonation activities; 25% by 1 month, 75% by 3 months, 88% by 6 months, and 100% by 1 year.