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Updated: Oct 10, 2026

Application of Long-term cultured Interferon-γ Enzyme-linked Immunospot Assay for Assessing Effector and Memory T Cell Responses in Cattle
Published on: July 11, 2015
[Immunological methods for the diagnosis of bovine tuberculosis--state of the art]
H Köhler1, G Martin, D Schimmel
1Bundesinstitut für gesundheitlichen Verbraucherschutz und Veterinärmedizin, Jena.
An overview is given about the most common immunological methods for the diagnosis of bovine tuberculosis. These methods are based on cell mediated immune reactions on the one hand (intradermal skin test, interferon-gamma-test, lymphocyte transformation test) or on antibody production against Mycobacterium bovis on the other hand (ELISA). The advantages and disadvantages of the methods as well as their specificity and sensitivity are discussed.
An overview is given about the most common immunological methods for the diagnosis of bovine tuberculosis. These methods are based on cell mediated immune reactions on the one hand (intradermal skin test, interferon-gamma-test, lymphocyte transformation test) or on antibody production against Mycobacterium bovis on the other hand (ELISA). The advantages and disadvantages of the methods as well as their specificity and sensitivity are discussed.
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