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Related Experiment Videos

Acute appendicitis caused by amebiasis.

N Gotohda1, S Itano, Y Okada

  • 1Department of Surgery, Terada Hospital, Nabari, Mie, Japan.

Journal of Gastroenterology
|November 21, 2000
PubMed
Summary

This case study details a rare instance of appendicitis caused by amebiasis. The patient recovered fully after an appendectomy, highlighting Entamoeba histolytica as a cause of appendicitis.

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Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Surgical Pathology

Background:

  • Appendicitis is a common surgical emergency, typically caused by bacterial infection.
  • Amebiasis, caused by Entamoeba histolytica, commonly presents as dysentery or liver abscesses.
  • Appendiceal amebiasis is an exceedingly rare manifestation of Entamoeba histolytica infection.

Observation:

  • A 45-year-old Japanese man presented with bloody stools, diagnosed as Entamoeba histolytica colitis via sigmoidoscopy and biopsy.
  • Four months later, he developed acute appendicitis symptoms, including a lower quadrant mass and severe pain.
  • Histopathological examination of the resected appendix revealed numerous Entamoeba histolytica trophozoites.

Findings:

  • The patient was diagnosed with acute appendicitis secondary to Entamoeba histolytica infection.

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  • Surgical intervention (appendectomy) was performed for the appendicitis.
  • Post-operative follow-up confirmed resolution of symptoms and absence of Entamoeba histolytica.

    • Implications:

    • This case underscores the importance of considering parasitic infections, such as amebiasis, in the differential diagnosis of appendicitis, especially in endemic areas or returning travelers.
    • Accurate diagnosis and timely surgical management are crucial for favorable outcomes in appendiceal amebiasis.
    • Further research may elucidate the specific mechanisms and risk factors contributing to this rare presentation.