Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of food additives on key bacterial taxa and the mucosa-associated microbiota in Crohn's disease. The ENIGMA study.

Gut microbes·2023
Same author

Letter: tofacitinib in biologic-experienced ulcerative colitis-a single-centre real-world experience in Australia.

Alimentary pharmacology & therapeutics·2021
Same author

Novel strain-level resolution of Crohn's disease mucosa-associated microbiota via an ex vivo combination of microbe culture and metagenomic sequencing.

The ISME journal·2021
Same author

Variants in ACTG2 underlie a substantial number of Australasian patients with primary chronic intestinal pseudo-obstruction.

Neurogastroenterology and motility·2018
Same author

Editorial: visceral fat as a predictor of post-operative recurrence of Crohn's disease-Authors' reply.

Alimentary pharmacology & therapeutics·2017
Same author

Visceral adiposity predicts post-operative Crohn's disease recurrence.

Alimentary pharmacology & therapeutics·2017

Related Experiment Video

Updated: Jul 26, 2026

Acupoint Needle-Embedding Combined with Ironing Therapy for Postoperative Pain After Anal Surgery
05:39

Acupoint Needle-Embedding Combined with Ironing Therapy for Postoperative Pain After Anal Surgery

Published on: June 23, 2023

Persistent pain and faecal urgency after stapled haemorrhoidectomy.

M J Cheetham1, N J Mortensen, P O Nystrom

  • 1Department of Surgery, St Mark's Hospital, Harrow, Middlesex, UK.

Lancet (London, England)
|November 21, 2000
PubMed
Summary

Stapled haemorrhoidectomy may lead to persistent pain and faecal urgency in 31% of patients. Muscle incorporation in the surgical doughnut may be a contributing factor, warranting further investigation into long-term outcomes.

More Related Videos

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
04:09

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors

Published on: February 13, 2026

Caudal-to-cranial Approach in Laparoscopic Right Hemicolectomy with Complete Mesocolon Excision and D3 Lymph Node Dissection
06:46

Caudal-to-cranial Approach in Laparoscopic Right Hemicolectomy with Complete Mesocolon Excision and D3 Lymph Node Dissection

Published on: January 9, 2026

Related Experiment Videos

Last Updated: Jul 26, 2026

Acupoint Needle-Embedding Combined with Ironing Therapy for Postoperative Pain After Anal Surgery
05:39

Acupoint Needle-Embedding Combined with Ironing Therapy for Postoperative Pain After Anal Surgery

Published on: June 23, 2023

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
04:09

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors

Published on: February 13, 2026

Caudal-to-cranial Approach in Laparoscopic Right Hemicolectomy with Complete Mesocolon Excision and D3 Lymph Node Dissection
06:46

Caudal-to-cranial Approach in Laparoscopic Right Hemicolectomy with Complete Mesocolon Excision and D3 Lymph Node Dissection

Published on: January 9, 2026

Area of Science:

  • Colorectal Surgery
  • Surgical Outcomes
  • Patient Recovery

Background:

  • Haemorrhoidectomy is a common treatment for haemorrhoids, often performed as day surgery.
  • While effective, traditional methods may involve a significant recovery period.
  • Stapled haemorrhoidectomy offers potential for reduced postoperative pain and shorter time off work.

Purpose of the Study:

  • To evaluate the long-term efficacy and functional outcomes of stapled haemorrhoidectomy.
  • To compare stapled haemorrhoidectomy with diathermy haemorrhoidectomy in a day-case setting.

Main Methods:

  • A pilot study followed by a randomized controlled trial involving 22 patients undergoing stapled haemorrhoidectomy.
  • Comparison with diathermy haemorrhoidectomy in a day-case setting.
  • Postoperative follow-up, including endoanal ultrasonography and anorectal physiology for symptomatic patients.

Main Results:

  • 31% of patients experienced persistent postoperative pain and faecal urgency for up to 15 months.
  • Muscle incorporation into the surgical doughnut was significantly associated with these symptoms (p=0.012).
  • No other significant differences in operative variables were identified.

Conclusions:

  • Stapled haemorrhoidectomy is associated with a high rate of persistent severe pain and faecal urgency.
  • Muscle incorporation in the surgical doughnut may play a role in these adverse outcomes.
  • Auditing long-term results across different centers is crucial to determine the frequency of this complication.