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The Collaborative Longitudinal Personality Disorders Study: baseline Axis I/II and II/II diagnostic co-occurrence
T H McGlashan1, C M Grilo, A E Skodol
1Yale Univeristy School of Medicine and Yale Psychiatric Institute and Department of Psychiatry, New Haven, CT 06520, USA.
Acta Psychiatrica Scandinavica
|November 23, 2000
Summary
This study examined diagnostic co-occurrences in personality disorders (PDs). Borderline PD and Schizotypal PD showed higher rates of co-occurring Axis I and II disorders compared to other groups.
Area of Science:
- Psychiatry
- Clinical Psychology
- Mental Health Research
Background:
- Understanding the co-occurrence of psychiatric diagnoses is crucial for effective treatment.
- The Collaborative Longitudinal Personality Disorders Study (CLPS) provides a robust dataset for examining these relationships.
Purpose of the Study:
- To describe the baseline diagnostic co-occurrence patterns of personality disorders (PDs) and Axis I disorders.
- To identify specific co-occurrence patterns within different personality disorder groups.
Main Methods:
- Utilized diagnostic interviews for DSM-IV Axis I and II disorders in 668 patients.
- Formed five patient groups: Schizotypal (STPD), Borderline (BPD), Avoidant (AVPD), Obsessive-Compulsive (OCPD), and Major Depressive Disorder (MDD) without PD.
Main Results:
- Patients had a mean of 3.4 lifetime Axis I diagnoses; STPD and BPD groups had more than AVPD, OCPD, and MDD groups.
- Significant Axis I co-occurrences included Social Phobia/AVPD, PTSD/BPD, and Substance Use/BPD.
- Significant PD co-occurrences involved STPD with Paranoid and Schizoid PDs; BPD with Antisocial and Dependent PDs.
Conclusions:
- Diagnostic co-occurrences largely aligned with expected base rates.
- Observed significant co-occurrence departures mirrored findings in existing literature.