Related Experiment Video

Updated: Jul 13, 2026

Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells
15:54

Combined DNA-RNA Fluorescent In situ Hybridization (FISH) to Study X Chromosome Inactivation in Differentiated Female Mouse Embryonic Stem Cells

Published on: June 14, 2014

X-Chromosome inactivation in cloned mouse embryos

K Eggan1, H Akutsu, K Hochedlinger

  • 1Whitehead Institute for Biomedical Research and Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, MA 02142, USA.

Science (New York, N.Y.)
|November 25, 2000
PubMed
Summary

Cloning resets epigenetic marks on X chromosomes in mouse embryos. The study shows that epigenetic marks can be removed and reestablished during cloning, influencing X chromosome inactivation patterns.

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