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Effect of left ventricular volume on results of coronary artery bypass grafting

R W Kim1, B S Ugurlu, D A Tereb

  • 1Department of Surgery, Yale University School of Medicine, New Haven, Connecticut 06510, USA.

The American Journal of Cardiology
|November 25, 2000
PubMed

Insights

Coronary artery bypass grafting improved angina and reduced left ventricular (LV) size in patients with ischemic cardiomyopathy and LV dilation. Ventricular size alone should not preclude surgical revascularization.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Heart Failure Research

Background:

  • Ischemic cardiomyopathy often involves left ventricular (LV) dilation.
  • The impact of LV dilation on outcomes after coronary artery bypass grafting (CABG) is debated.
  • Surgical revascularization is a key treatment for ischemic heart disease.

Purpose of the Study:

  • To evaluate the outcomes of CABG in patients with ischemic cardiomyopathy and significant LV dilation.
  • To determine if LV size is a contraindication for surgical revascularization.
  • To assess the effect of CABG on angina symptoms, survival, and LV remodeling.

Main Methods:

  • Retrospective analysis of patients undergoing CABG.
  • Inclusion criteria: ischemic cardiomyopathy with significant LV dilation.
  • Assessment of angina symptoms, operative mortality, medium-term survival, LV ejection fraction, and LV chamber dimensions.

Main Results:

  • Patients experienced improved angina symptoms post-CABG.
  • Operative and medium-term survival rates were acceptable.
  • A trend toward improved LV ejection fraction was observed.
  • Significant reduction in LV chamber size was achieved.

Conclusions:

  • CABG can be safely performed in patients with ischemic cardiomyopathy and LV dilation.
  • Improved clinical outcomes and LV remodeling suggest benefits of revascularization.
  • LV chamber size should not be the sole factor for excluding patients from surgical revascularization.

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