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Papid Growing Fibroadenoma in an Adlescent
1First Department of Surgery, Kochi Medical School, KoHasu, Oko-cho, Nankoku 783-8505, Japan.
A rapidly growing fibroadenoma in a young girl was linked to estrogen sensitivity. Immunohistochemical staining revealed estrogen receptor positivity in tumor cells, explaining its accelerated growth during menses.
Area of Science:
- Oncology
- Endocrinology
- Pathology
Background:
- Fibroadenomas are common benign breast tumors, particularly in young women.
- Rapid growth of fibroadenomas can cause patient concern and necessitate intervention.
Purpose of the Study:
- To report a case of rapidly growing fibroadenoma in a pediatric patient.
- To investigate the potential factors contributing to the accelerated tumor growth.
Main Methods:
- Clinical examination and ultrasound for initial diagnosis.
- Surgical excision (lumpectomy) for tumor removal.
- Histopathological analysis and immunohistochemical staining for estrogen receptor expression.
Main Results:
- A 13-year-old girl presented with a rapidly enlarging left breast mass.
- The fibroadenoma increased 50% in volume over four months, correlating with menstrual cycles.
- Immunohistochemistry confirmed positive estrogen receptor staining in glandular epithelial cells of the fibroadenoma.
Conclusions:
- The estrogen sensitivity of the fibroadenoma is a likely cause of its rapid growth.
- This case highlights the importance of considering hormonal influences in benign breast tumor behavior.
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