Related Experiment Video
Updated: Jul 22, 2026
10:35
Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
Radiation Complications Following Breast Conserving Therapy
1Department of Radiology, University of Tokushima, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan.
Breast Cancer (Tokyo, Japan)
|November 25, 2000
Summary
Radiotherapy following breast conserving surgery for early breast cancer is safe and effective. Complications were minimal, demonstrating radiotherapy
Area of Science:
- Oncology
- Radiation Oncology
- Surgical Oncology
Background:
- Breast conserving therapy (BCT) is a standard treatment for early breast cancer in Japan.
- Indications and standardized procedures for radiotherapy after BCT are not yet established.
- This study evaluates complications of radiotherapy in patients undergoing BCT.
Purpose of the Study:
- To assess the safety and efficacy of radiotherapy following breast conserving surgery for early breast cancer.
- To evaluate radiation-induced complications in patients treated with BCT and radiotherapy.
- To determine if radiotherapy adverse reactions impact the benefits of BCT.
Main Methods:
- Retrospective analysis of 60 women with stage I or II breast cancer treated between October 1989 and March 1996.
- Patients received radiation therapy after breast conserving surgery.
- Radiation morbidity was scored using RTOG/EORTC criteria; median follow-up was 27 months.
Main Results:
- Only one local recurrence was observed, attributed to an extended intraductal component.
- No distant metastasis or deaths occurred.
- Transient dermal reactions were noted, but no cosmetic issues or serious complications in adjacent organs (lungs, ribs, heart) were found.
Conclusions:
- Adverse reactions from radiotherapy in BCT are minimal and do not outweigh the treatment benefits.
- Radiotherapy can be safely integrated into breast conserving therapy for early breast cancer.
- These findings support the application of radiotherapy in BCT without hesitation.
Related Concept Videos
02:59Biological Effects of Radiation
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they produce ions...
01:17Radiation: Applications
The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
The average...
01:30Radiological Investigation I: X-ray and CT
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and the...
01:30Radiological Investigation II: MRI and Ventilation Perfusion Scan
Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
01:13Radiological Investigation III: Pulmonary Angiogram and PET Scan
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
01:24Healing II: Complications
Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...