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Hydroxychloroquine retinopathy despite regular ophthalmologic evaluation: a consecutive series
D Bienfang1, J S Coblyn, M H Liang
1Department of Surgery, Harvard Medical School, Brigham and Women's Hospital, and Robert B. Brigham Multipurpose Arthritis and Musculoskeletal Disease Center, Boston, Massachusetts, USA.
The Journal of Rheumatology
|November 28, 2000
Abstract:
We describe a consecutive series of patients with hydroxychloroquine (HCQ) retinopathy. Their clinical features illustrate that with normal renal function there is no threshold for total dosage for HCQ toxicity; that color vision testing is important; that almost all patients complain of altered central vision as their first symptom; and that a normal optic fundus does not exclude the diagnosis. Finally, HCQ retinopathy may progress even when the agent is stopped.