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The calcium-phosphate-induced fusion of human erythrocytes
Sheremetyev YuA1, I L Fomin, Suslov FYu
1State Agricultural Academy, Nizhny Novgorod, Russia.
Membrane & Cell Biology
|November 28, 2000
Abstract:
The calcium-phosphate-induced fusion of normal human erythrocytes with those having increased (above physiological) levels of intracellular ATP was studied. Fusion of erythrocytes was markedly enhanced in the case of increased content of intracellular ATP. Fusion of such erythrocytes results in formation of giant cells up to 130 microm in diameter. Dithiothreitol practically completely inhibited fusion of erythrocytes with normal ATP content and markedly lowered it between those with increased ATP content.